"Well, when are you ready for the baby?" - this question invariably leads Andrei and Lena out of themselves. "I do not understand," the girl wearily drops her hands. - We have passed all the doctors, everything is in order. But I'm not pregnant. I do not know why. And no one knows. Friends mutter comforting words that, they say, it's all psychology and just did not come the right moment. Or maybe it's just that the man is inappropriate? However, American scientists seem to have managed to find an explanation for such anomalies. A group of researchers from New York believes that the whole matter is in a specific gene mutation. In an article published in the journal Scientific Reports, they explain: the root of all misfortunes lurks in the DNA chain. And specifically - in the gene NLRP2.causes of infertilityPhoto:GwttyImagesIf a woman does not have this gene, there is a problem: she cannot get pregnant, or the pregnancy ends in miscarriage, sometimes at the stage when the embryo has not yet attached. Other deviations also occur: abnormal development of the placenta, for example. And if she does manage to get pregnant and carry a child to term, then there is a very high probability that the baby will be born with deviations. - Women who have this mutation are healthy in all other physical aspects. Therefore, they do not know that they have these mutations, and it is because of them that they cannot become mothers, - says Sangeeta Mahadevan, head of the study, doctor of the Baylor Medicine College. The scientists made their conclusions based on experiments conducted on mice. Not a single female whose DNA had a mutation of the NLRP gene was able to give birth to healthy offspring. Moreover, when the researchers tried to artificially grow an embryo from the egg of a mutant mouse, it simply did not develop. “Even IVF will not help such women. They are genetically incapable of bearing offspring,” admits Dr. Mahadevan. If these disappointing findings are confirmed in further experiments, scientists will have a new task: how to correct this mutation to give every woman the opportunity to bear a child.

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